Integrated Data Nodes of Regulation (IDARE) is an active open sourced project envisioned to provide a simple and familiar way of putting expression and regulatory data in context of metabolism.

We show the general applicability of the IDARE concept with two distinct data sets, one from human SGBS adipocyte differentiation related (Phenotype comparison) data and the other from HUVEC multiple transcription factor binding data (Overlay on metabolic network). The utility brought by IDARE relies on providing a direct way of hypothesizing and interpreting the metabolic outcome of regulation, through visualizing data-customized gene metanodes linked to metabolic pathways and properties.

The web tool is built on top of open sourced components cytoscapeweb, jQuery and relies on HTML5 technologies. A workflow is provided for local data adaptation and/or custom enhancements. Please see our source repository and user guide for more details.